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X-WR-CALDESC:Events for Department of Bioengineering
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DTSTART;TZID=America/New_York:20201104T120000
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SUMMARY:BioE Seminar Series Presents: Leyla Esfandiari
DESCRIPTION:Leyla Esfandiari\, Ph.D. \nAssistant professor\, Department of Electrical Engineering and Biomedical Engineering\, University of Cincinnati\, Cincinnati OH \n“Electrokinetically Driven Micro-pores for Minimally-Invasive Cancer Diagnosis” \nAbstract:  \nEarly detection of cancer is essential for improved long-term survival of patients. Traditionally\, invasive and costly procedures\, such as surgical tissue biopsies have been used for cancer screening. However\, over the past few decades\, advancements in microfluidics and lab-on-a-chip approaches have been made to develop minimally invasive and miniaturized platforms to detect the circulating cancer biomarkers from biofluids. Among circulating biomarkers\, small extracellular vesicles (exosomes)\, have drawn a great deal of attention due to their high abundance in all biofluids and their enriched and highly stable gene regulatory content including micro-RNAs. Tumor-derived exosomes have also shown potential for early diagnosis and prognosis of cancer in difficult to access tumor sites. However\, because of the complex nature of biofluids and the heterogeneous physicochemical properties of exosomes\, their accurate isolation and characterization raises significant challenges in clinical settings. To address these challenges\, we have developed a simple\, yet powerful electrokinetically driven micro-pore device capable of rapid and label-free purification of exosomes from biofluids by applying a significantly low electric field. The device is also tailored with an impedance measurement module to further characterize exosomes based on their unique dielectric properties. We have further used the micro-pores for rapid detection of sequence-specific circulating micro-RNAs with high sensitivity and accuracy.  \nBIOGRAPHY: \nDr. Leyla Esfandiari is a tenure-track assistant professor with dual appointment in the departments of Electrical Engineering and Biomedical Engineering at University of Cincinnati (UC). At UC\, she is the principal investigator of the Integrative BioSensing Laboratory (IBL) with the main focus on development of nano/micro-scaled bioanalytical tools\, organic bioelectronics\, and microfluidics for medical and environmental applications. She has been the member of Cincinnati Cancer Center and the Center for Stem Cell and Organoid Medicine (CuSTOM) at Cincinnati Children’s Hospital. Her research has been supported by the National Institute of Health/ National Cancer Institute\, National Science Foundation\, Department of Transportation (DOT) and Office of Research at UC.  \nDr. Esfandiari completed her doctoral degree in bioengineering from University of California Los Angeles (UCLA); and earned her MSc in biomedical engineering from University of California Irvine. While at UCLA\, she conducted research at the California Nano-System Institution (CNSI)\, the College of Medicine and the College of Engineering and Applied Sciences. Besides academic training\, she has had three years of experience in industry.  \nDr. Esfandiari has won numerous awards including UC College of Engineering and Applied Science Distinguished Research Award\, the William E. Restemeyer Teaching Excellence Award\, UC Faculty Development Award\, UCLA Unrestricted Fellowship\, UC Irvine Kleist Fellowship\, NSF Fellowship\, and Boeing Scholarship.   \nIf interested\, please email Elizabeth Chesley at e.chesley@northeastern.edu for the seminar link.
URL:https://bioe.northeastern.edu/event/bioe-seminar-series-presents-leyla-esfandiari/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
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DTSTART;TZID=America/New_York:20201109T080000
DTEND;TZID=America/New_York:20201109T090000
DTSTAMP:20260505T222041
CREATED:20201103T203835Z
LAST-MODIFIED:20201103T203835Z
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SUMMARY:Bioengineering Graduate School Webinar
DESCRIPTION:Join current faculty\, staff and current students to learn more about graduate program options in Bioengineering \nMonday\, November 9 \n8:00 AM EST \nhttps://us02web.zoom.us/webinar/register/WN_Acz1Ke3XSpGQ4zOVBzw-vA
URL:https://bioe.northeastern.edu/event/bioengineering-graduate-school-webinar/
ORGANIZER;CN="Graduate School of Engineering":MAILTO:coe-gradadmissions@northeastern.edu
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DTSTART;TZID=America/New_York:20201118T120000
DTEND;TZID=America/New_York:20201118T130000
DTSTAMP:20260505T222041
CREATED:20200930T224251Z
LAST-MODIFIED:20200930T224251Z
UID:2081-1605700800-1605704400@bioe.northeastern.edu
SUMMARY:BioE Seminar Series Presents: Christoph Juchem
DESCRIPTION:Christoph Juchem\, Ph.D. \nAssociate Professor in the Departments of Biomedical Engineering and Radiology\, Columbia University\, New York New York \n“Magnetic Resonance Imaging and B0 Shimming with the Dynamic Multi-Coil Technique (DYNAMITE)” \nABSTRACT:   \nIn my talk\, I will present a technique for B0 magnetic field control that is based on the combination of fields generated by a matrix of small\, individually driven generic coils. This multi-coil approach enables the accurate generation of simple and complex magnetic field shapes in a flexible fashion. B0 shimming with the dynamic multi-coil technique (DYNAMITE) outperforms conventional methods based on spherical harmonic functions and provides unrivaled magnetic field homogeneity in mouse\, rat and human brain. Along with the efficiency gains of DYNAMITE shimming compared to spherical harmonic approaches\, the multi-coil concept has the potential to replace conventional shim systems that are based on sets of dedicated SH coils and allow optimal object-specific shim solutions. The technology furthermore lends itself to spatial encoding. I will present MRI results\, including concomitant imaging and B0 shimming\, in which all fields are purely DYNAMITE-based and conclude with the first realization of DYNAMITE MRI of the in vivo human brain. The obtained image fidelity is comparable to MRI with conventional gradient coils\, paving the way for full-fledged human DYNAMITE MRI systems. \nBIOGRAPHY: \nDr. Juchem is an Associate Professor in the Departments of Biomedical Engineering and Radiology at Columbia University. In his research\, he develops technology and methods to realize the full clinical potential of magnetic resonance applications. Dr. Juchem has 18 years of experience in developing and conducting in vivo MR experiments at 3.0-11.7 Tesla field in humans and animal models. He served as Co-Director of Yale University’s 7T Brain MR Spectroscopy Core\, Chair of the ISMRM Engineering Study group\, and he serves on the editorial board of NMR in Biomedicine. \nIf interested in attending\, please email Elizabeth Chesley at e.chesley@northeastern.edu for the Zoom link.
URL:https://bioe.northeastern.edu/event/bioe-seminar-series-presents-christoph-juchem/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
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