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DTSTART;TZID=America/New_York:20211020T120000
DTEND;TZID=America/New_York:20211020T130000
DTSTAMP:20260424T081617
CREATED:20211014T193952Z
LAST-MODIFIED:20211014T193952Z
UID:2523-1634731200-1634734800@bioe.northeastern.edu
SUMMARY:BioE Seminar Series Presents: Victor Baracos
DESCRIPTION:Victor Barocas\, Ph.D. \nProfessor\, Department of Biomedical Engineering\, University of Minnesota \n“Computer Modeling of Ascending Thoracic Aortic Aneurysm\, or How I Learned Accept Change\, Variability\, and Failure as a Part of Life” \nWednesday\, October 20th\, 2021 \n12:00 pm – 1:00 pm EST \nABSTRACT: \nAscending Thoracic Aortic Aneurysm (ATAA)\, a condition in which the section of the aorta immediately adjacent to the heart becomes enlarged\, presents a major clinical challenge. The disease is largely asymptomatic and harmless unless the tissue dissects or ruptures\, in which case severe consequences almost always ensue. Repair surgery is costly and carries a 2-4% chance of patient mortality. The challenge\, then\, is to decide whether to perform the surgery when the patient might be just fine without it. Current guidelines are based primarily on aneurysm size\, but numerous other potential biomarkers exist\, including other geometric measures\, mechanical measures\, genetic factors\, and biofluidic factors; some of these are directly attainable in the clinic\, and others are attainable through patient specific computer models. Our group is exploring ATAA with a combination of computer and experimental models in hope of identifying better ways to assess patient risk. The seminar will discuss computer models at both the tissue and the structural scale\, how they relate to experimental studies\, and where I see us and the field going in the future \nBIOGRAPHY: \nVictor Barocas is a Professor of Biomedical Engineering at the University of Minnesota\, where he has taught since 2000. His research focuses on soft-tissue biomechanics\, with applications in the cardiovascular and musculoskeletal systems. Experimental work focuses on novel techniques to measure tissue mechanical properties\, particularly in heterogeneous tissues\, and his computational work focuses on structural and multiscale models of tissue mechanics. He has served for the last ten years as co-Editor-in-Chief of the ASME Journal of Biomechanical Engineering. \nInterested in attending? Email Liz at e.chesley@northeastern.edu for the Zoom link.
URL:https://bioe.northeastern.edu/event/bioe-seminar-series-presents-victor-baracos/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211013T120000
DTEND;TZID=America/New_York:20211013T130000
DTSTAMP:20260424T081617
CREATED:20211001T003614Z
LAST-MODIFIED:20211001T003614Z
UID:2493-1634126400-1634130000@bioe.northeastern.edu
SUMMARY:BioE Seminar Series Presents: Jared Auclair
DESCRIPTION:Jared Auclair Ph.D. \nAssociate Dean of Professional Program and Graduate Affairs\, College of Science\, Northeastern University  \n  \n“Northeastern’s COVID19 Testing Response in 2020 through Today” \nBehrakis 010  \n  \nABSTRACT:   \nIn March of 2020\, Northeastern made the announcement to go to full online teaching modalities in response to the SARS-CoV-2 pandemic.  A few short weeks later\, Northeastern sent all students home and closed the campus.  Almost immediately after the closing of the University a reopening committee went to work to plan to reopen campus for AY20/21.  As part of the reopening committee\, a Testing Task Force was instituted.  In this talk\, I’ll give some insight into the discussions that lead to our AY20/21 testing strategy\, how we leveraged the Biopharmaceutical Analysis and Training Laboratory\, as well as share some of the data we have collected over the last 12 months.  Then\, I’ll transition to our thought process regarding Fall 2021 testing\, highlighting the differences from our AY20/21 strategy.  I will also share some of our variant and next-generation sequencing data.    \nBIOGRAPHY: \nJared R. Auclair is currently the Associate Dean of Professional Program and Graduate Affairs in the College of Science at Northeastern University and Associate Teaching Professor in the department of chemistry and chemical biology.  In addition\, Dr. Auclair is the Director of the Biopharmaceutical Analysis Laboratory (BATL)\, the Asia-Pacific Economic Cooperation Center of Regulatory Excellence in Biotherapeutics and Advanced Therapies\, and oversees the International Council for Harmonisation training.  Lastly\, Prof. Auclair serves as the Technical Supervisor for the Life Science Testing Center at Northeastern University\, which is a state and CLIA-certified lab.  Dr. Auclair collaborates with both academic researchers\, industry and government in the area of biopharmaceutical and cell/gene therapy development and analysis.  He has expertise in mol. biology\, protein biochemistry\, analytical chemistry\, protein crystallography\, and biological mass spectrometry; and is interested in use-inspired research for the biotechnology industry
URL:https://bioe.northeastern.edu/event/bioe-seminar-series-presents-jared-auclair/
LOCATION:010 Behrakis\, 360 Huntington Ave\, Boston\, MA\, 02115\, United States
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
GEO:42.3396156;-71.0886534
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=010 Behrakis 360 Huntington Ave Boston MA 02115 United States;X-APPLE-RADIUS=500;X-TITLE=360 Huntington Ave:geo:-71.0886534,42.3396156
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211012T143000
DTEND;TZID=America/New_York:20211012T153000
DTSTAMP:20260424T081617
CREATED:20211007T174838Z
LAST-MODIFIED:20211012T173605Z
UID:2511-1634049000-1634052600@bioe.northeastern.edu
SUMMARY:Launch of ALLIED Project
DESCRIPTION:The ALLIED (Allies for Leading\, Learning\, Inclusion\, and Education of Disabilities) Project at Northeastern University is working to open discussions and raise awareness about disabilities on campus. This ALLIED program is taking the first steps towards connecting disability services and planting the seed for future disability programming. \nIn-person launch happening in 655 ISEC (Interdisciplinary Science & Engineering Complex). \nYou can also join us on Zoom: https://northeastern.zoom.us/j/98915783606 \n 
URL:https://bioe.northeastern.edu/event/launch-of-allied-project/
CATEGORIES:use the department, audience, and topic lists
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20211006T120000
DTEND;TZID=America/New_York:20211006T130000
DTSTAMP:20260424T081617
CREATED:20210930T215401Z
LAST-MODIFIED:20211001T003703Z
UID:2490-1633521600-1633525200@bioe.northeastern.edu
SUMMARY:BioE Seminar: The Case for Diversity and Inclusion\, From An Engineer’s Perspective
DESCRIPTION:Department of Bioengineering  \nSeminar Series  \nKarl W. Reid\, Ed.D.\, CDP   \nSenior Vice Provost and Chief Inclusion Officer\, Northeastern University  “The Case for Diversity and Inclusion\, From An Engineer’s Perspective”  \nBehrakis 010  \nABSTRACT:  \nThis talk makes the case for why diversity and inclusion matter and offers steps to creating more equitable and inclusive campuses and workplaces. \nBIOGRAPHY:  \nDr. Karl W. Reid was appointed Senior Vice Provost and Chief Inclusion Officer at Northeastern University on April  1\, 2021. He also holds the title of Professor of Practice in the Graduate School of Education in the College of  Professional Studies. Prior to joining Northeastern\, Dr. Reid served for seven years as the Executive Director of the  National Society of Black Engineers (NSBE)\, marking his return to the organization that gave him his first major leadership experience 32 years earlier. A certified diversity professional\, Dr. Reid has been a leading national advocate for diversity and inclusion\, and increasing college access\, opportunity\, and success for low-income and minority youth. \nDr. Reid came to NSBE from the United Negro College Fund (UNCF)\, where he oversaw new program development\, research\, and capacity building for the organization’s 37 historically black colleges and universities and held the title of Senior Vice President for Research\, Innovation\, and Member College  Engagement. Before his service at UNCF\, he worked in positions of progressive responsibility to increase diversity at his alma mater\, the Massachusetts Institute of Technology (MIT)\, which he left as Associate Dean of Undergraduate Education and Director of the Office of Minority Education. While working at MIT as Director of Engineering Outreach Programs\, Dr. Reid earned his Doctor of Education degree at Harvard University. His dissertation explored the interrelationship of race\, identity\, and academic achievement for African American males in college. He is the author of “Working Smarter\, Not Just Harder: Three Sensible Strategies for  Succeeding in College…and Life.” Dr. Reid is also a founding member of the 50K Coalition\, a national effort to produce 50\,000 diverse engineering graduates annually by 2025. \nDr. Reid was born in the Bronx\, New York\, and grew up in Roosevelt\, New York\, a mostly working-class\, African-American community on Long Island. The high value his parents placed on education\, and his admission to a well-resourced\, magnet high school near Roosevelt\, put him on a track to follow his older brother to MIT\, where he earned his undergraduate and master’s degrees in Materials Science and Engineering and was a Tau Beta Pi Scholar. He credits his membership in the NSBE chapter at MIT  with giving a vital boost to his self-confidence and leadership skills. He joined the Society during his freshman year\, was elected chapter Vice President during his junior year\, and subsequently served as NSBE National  Chair. \nAfter graduating from MIT\, Dr. Reid worked in the computer industry for 12 years in product management\, marketing\, sales\, and consulting. In 1991\, five years into a successful career in sales and marketing with IBM Corporation\, Dr. Reid read Jonathan Kozol’s “Savage Inequalities\,” a seminal book about educational disparities in the U.S.\, which sparked his passion for bringing about positive change through the education of African Americans and other underserved populations. \nDr. Reid sits on the National Council for Expanding American Innovation at the US Patent and  Trademark Office; the Committee on Addressing the Underrepresentation of Women of Color in Technology at the National Academy of Engineering; the American Society for Civil Engineers Industrial Leaders Council;  the Dean’s advisory cabinets for the Harvard University School of Engineering and Applied Sciences and the University of Michigan College of Engineering. He holds memberships in the American Society for Engineering Education and the Council of Engineering and Scientific Society Executives. \nHe is a frequent contributor to the national diversity engineering dialogue and author of several commentary pieces\, and he has been quoted in numerous articles in publications such as Forbes\, The Wall Street Journal\, U.S.  News & World Report\, and The Hechinger Report.
URL:https://bioe.northeastern.edu/event/bioe-seminar-the-case-for-diversity-and-inclusion-from-an-engineers-perspective/
LOCATION:010 Behrakis\, 360 Huntington Ave\, Boston\, MA\, 02115\, United States
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
GEO:42.3396156;-71.0886534
X-APPLE-STRUCTURED-LOCATION;VALUE=URI;X-ADDRESS=010 Behrakis 360 Huntington Ave Boston MA 02115 United States;X-APPLE-RADIUS=500;X-TITLE=360 Huntington Ave:geo:-71.0886534,42.3396156
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210225T140000
DTEND;TZID=America/New_York:20210225T150000
DTSTAMP:20260424T081617
CREATED:20210209T200948Z
LAST-MODIFIED:20210217T220646Z
UID:2260-1614261600-1614265200@bioe.northeastern.edu
SUMMARY:Engineers Week: Laser Cutting 101
DESCRIPTION:The Bioengineering Department presents speaker Noah Joseph for this year’s Engineers Week events. \n\nLocation: This event is virtual\, free\, and open to the public. \nJoin Zoom Meeting\nhttps://northeastern.zoom.us/j/93306770038?pwd=c1JqWHhUZFR2bFNvVG1DdnR5akI5dz09 \nMeeting ID: 933 0677 0038\nPasscode: 709079\nOne tap mobile\n+19292056099\,\,93306770038#\,\,\,\,*709079# US (New York)\n+13017158592\,\,93306770038#\,\,\,\,*709079# US (Washington DC) \n\nLaser Cutting 101 \nNoah JosephLab Technician\, Northeastern University \nNoah Joseph\, Lab Technician\, Northeastern University \nTake a tour of the newly renovated 3D Print room of the Bioengineering Capstone Collaborative. Briefly explore different 3D printing technologies (Fused Deposition Modeling\, Stereolithography\, Fused Filament Fabrication\, and Continuous Filament Fabrication). Then\, take a deep dive into the world of laser cutting with the Boss Laser LS-1420 machine. Learn about how this CO2 laser cutter works and what materials can be cut and engraved. We’ll walk through the process of bringing an idea from file to real-world object. \nNoah Joseph earned his undergraduate degree in Mechanical Engineering from Brown University in 2018. Since September 2018\, he has worked as a Lab Technician for both Northeastern’s Bioengineering department as well as the Michael J. and Ann Sherman Center for Engineering Entrepreneurship Education. \nNoah oversees the day-to-day operations of the Bioengineering Capstone Collaborative (BCC)\, which is a workspace that serves bioengineering undergraduates\, graduate students\, and faculty. He maintains and operates instrumentation in the BCC\, which include a suite of 3D printers\, a laser cutter\, hand tools\, power tools\, and various electronic fabrication/testing equipment. \nDownload Flyer (pdf)
URL:https://bioe.northeastern.edu/event/engineers-week-laser-cutting-101/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20210222T133000
DTEND;TZID=America/New_York:20210222T143000
DTSTAMP:20260424T081617
CREATED:20210209T150008Z
LAST-MODIFIED:20210217T220307Z
UID:2257-1614000600-1614004200@bioe.northeastern.edu
SUMMARY:Engineers Week: 'What's the big deal about COVID-19 variants and why should we care?'
DESCRIPTION:The Bioengineering Department presents speaker Lee Makowski for this year’s Engineers Week events. \n\nLocation: This event is virtual\, free\, and open to the public. \nJoin Zoom Meeting \nhttps://northeastern.zoom.us/j/95153700231?pwd=R0ZMUG50Tm9tRDRqQnZZWjFheXJXdz09 \nMeeting ID: 951 5370 0231\nPasscode: 312358\nOne tap mobile\n+13017158592\,\,95153700231#\,\,\,\,*312358# US (Washington DC)\n+13126266799\,\,95153700231#\,\,\,\,*312358# US (Chicago) \n\n‘What’s the big deal about COVID-19 variants and why should we care?’ \nLee Makowski Professor and Department Chair\, Department of Bioengineering \nLee Makowski\, Professor and Department Chair\, Department of Bioengineering \nVaccines developed to protect against infection with SARS CoV-2 virus are less effective against some viral variants that have recently arisen.  How is that possible\, and what can we do about it?  In this presentation I will outline how vaccines are designed\, why some variants can evade neutralization by the vaccines and others cannot\, and discuss why I believe there will be ‘booster’ vaccines developed against the variants\, probably available by late summer. \nDr. Makowski is Professor and Chair of Bioengineering and Professor of Chemistry and Chemical Biology at Northeastern University.  He has a BS in Physics from Brown University and Ph.D. in Electrical Engineering from MIT.  His research interests focus on the molecular basis of biological processes. In 2010\, he moved from Argonne National Laboratory where he was Biosciences Division Director and Senior Scientist to Northeastern University where he accepted a joint appointment in Electrical and Computer Engineering and Chemistry and Chemical Biology.  In January 2014 Dr. Makowski was appointed as Interim Chair of the newly established Department of Bioengineering and became Chair in September 2015.  His current research program aspires to understand the inception and progression of Alzheimer’s disease.  With the emergence of COVID-19\, he redirected his efforts to try to understand the array of unexpected extrapulmonary impacts SARS CoV-2 has on some patients. \nDownload Flyer (pdf)
URL:https://bioe.northeastern.edu/event/engineers-week-whats-the-big-deal-about-covid-19-variants-and-why-should-we-care/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201202T120000
DTEND;TZID=America/New_York:20201202T130000
DTSTAMP:20260424T081617
CREATED:20200930T224350Z
LAST-MODIFIED:20200930T224350Z
UID:2082-1606910400-1606914000@bioe.northeastern.edu
SUMMARY:BioE Seminar Series Presents: Jessica Wagenseil
DESCRIPTION:Jessica Wagenseil\, Ph.D. \nAssociate Professor\, Department of Mechanical Engineering and Materials Science\, Washington University\, St. Louis MO \n“Elastin mechanobiology in aortic development” \nABSTRACT:   \nThe extracellular matrix protein\, elastin\, provides reversible extensibility to the aorta that is critical for proper function of the cardiovascular system. Elastin is deposited during late embryonic and early postnatal growth\, at the same time that blood pressure and flow are increasing. This relationship suggests that mechanobiological signals for elastin deposition are linked to hemodynamic forces. I will discuss how reduced or absent elastin affects aortic mechanics\, cardiovascular hemodynamics\, and aortic wall development in genetically modified mouse models. I will also discuss how altered hemodynamics\, specifically reduced blood flow\, affects elastin amounts\, aortic mechanics\, and wall development in developing chick embryos. I will introduce mathematical models that we use to better understand the cause and effect relationships between elastin amounts and cardiovascular hemodynamics. The combination of experimental work in diverse animal models and mathematical modeling will advance our understanding of how the aortic wall is constructed to provide appropriate extensibility for normal cardiovascular function. The knowledge will aid in designing tissue-engineered arteries and in the treatment of cardiovascular diseases associated with elastin defects \nBIOGRAPHY: \nDr. Wagenseil joined the Mechanical Engineering and Materials Science Department at Washington University in 2013. She was previously in the Biomedical Engineering Department at Saint Louis University. She got her B.S. at UC San Diego and did her doctoral and postdoctoral training at Washington University. Dr. Wagenseil studies vascular mechanics focusing on the extracellular matrix in development and disease. Dr. Wagenseil received the 2020 Renato Iozzo Award from the American Society for Matrix Biology \nIf interested in attending\, please email Elizabeth Chesley at e.chesley@northeastern.edu for the Zoom link.
URL:https://bioe.northeastern.edu/event/bioe-seminar-series-presents-jessica-wagenseil/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201118T120000
DTEND;TZID=America/New_York:20201118T130000
DTSTAMP:20260424T081617
CREATED:20200930T224251Z
LAST-MODIFIED:20200930T224251Z
UID:2081-1605700800-1605704400@bioe.northeastern.edu
SUMMARY:BioE Seminar Series Presents: Christoph Juchem
DESCRIPTION:Christoph Juchem\, Ph.D. \nAssociate Professor in the Departments of Biomedical Engineering and Radiology\, Columbia University\, New York New York \n“Magnetic Resonance Imaging and B0 Shimming with the Dynamic Multi-Coil Technique (DYNAMITE)” \nABSTRACT:   \nIn my talk\, I will present a technique for B0 magnetic field control that is based on the combination of fields generated by a matrix of small\, individually driven generic coils. This multi-coil approach enables the accurate generation of simple and complex magnetic field shapes in a flexible fashion. B0 shimming with the dynamic multi-coil technique (DYNAMITE) outperforms conventional methods based on spherical harmonic functions and provides unrivaled magnetic field homogeneity in mouse\, rat and human brain. Along with the efficiency gains of DYNAMITE shimming compared to spherical harmonic approaches\, the multi-coil concept has the potential to replace conventional shim systems that are based on sets of dedicated SH coils and allow optimal object-specific shim solutions. The technology furthermore lends itself to spatial encoding. I will present MRI results\, including concomitant imaging and B0 shimming\, in which all fields are purely DYNAMITE-based and conclude with the first realization of DYNAMITE MRI of the in vivo human brain. The obtained image fidelity is comparable to MRI with conventional gradient coils\, paving the way for full-fledged human DYNAMITE MRI systems. \nBIOGRAPHY: \nDr. Juchem is an Associate Professor in the Departments of Biomedical Engineering and Radiology at Columbia University. In his research\, he develops technology and methods to realize the full clinical potential of magnetic resonance applications. Dr. Juchem has 18 years of experience in developing and conducting in vivo MR experiments at 3.0-11.7 Tesla field in humans and animal models. He served as Co-Director of Yale University’s 7T Brain MR Spectroscopy Core\, Chair of the ISMRM Engineering Study group\, and he serves on the editorial board of NMR in Biomedicine. \nIf interested in attending\, please email Elizabeth Chesley at e.chesley@northeastern.edu for the Zoom link.
URL:https://bioe.northeastern.edu/event/bioe-seminar-series-presents-christoph-juchem/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201104T120000
DTEND;TZID=America/New_York:20201104T130000
DTSTAMP:20260424T081617
CREATED:20200930T224121Z
LAST-MODIFIED:20200930T224121Z
UID:2080-1604491200-1604494800@bioe.northeastern.edu
SUMMARY:BioE Seminar Series Presents: Leyla Esfandiari
DESCRIPTION:Leyla Esfandiari\, Ph.D. \nAssistant professor\, Department of Electrical Engineering and Biomedical Engineering\, University of Cincinnati\, Cincinnati OH \n“Electrokinetically Driven Micro-pores for Minimally-Invasive Cancer Diagnosis” \nAbstract:  \nEarly detection of cancer is essential for improved long-term survival of patients. Traditionally\, invasive and costly procedures\, such as surgical tissue biopsies have been used for cancer screening. However\, over the past few decades\, advancements in microfluidics and lab-on-a-chip approaches have been made to develop minimally invasive and miniaturized platforms to detect the circulating cancer biomarkers from biofluids. Among circulating biomarkers\, small extracellular vesicles (exosomes)\, have drawn a great deal of attention due to their high abundance in all biofluids and their enriched and highly stable gene regulatory content including micro-RNAs. Tumor-derived exosomes have also shown potential for early diagnosis and prognosis of cancer in difficult to access tumor sites. However\, because of the complex nature of biofluids and the heterogeneous physicochemical properties of exosomes\, their accurate isolation and characterization raises significant challenges in clinical settings. To address these challenges\, we have developed a simple\, yet powerful electrokinetically driven micro-pore device capable of rapid and label-free purification of exosomes from biofluids by applying a significantly low electric field. The device is also tailored with an impedance measurement module to further characterize exosomes based on their unique dielectric properties. We have further used the micro-pores for rapid detection of sequence-specific circulating micro-RNAs with high sensitivity and accuracy.  \nBIOGRAPHY: \nDr. Leyla Esfandiari is a tenure-track assistant professor with dual appointment in the departments of Electrical Engineering and Biomedical Engineering at University of Cincinnati (UC). At UC\, she is the principal investigator of the Integrative BioSensing Laboratory (IBL) with the main focus on development of nano/micro-scaled bioanalytical tools\, organic bioelectronics\, and microfluidics for medical and environmental applications. She has been the member of Cincinnati Cancer Center and the Center for Stem Cell and Organoid Medicine (CuSTOM) at Cincinnati Children’s Hospital. Her research has been supported by the National Institute of Health/ National Cancer Institute\, National Science Foundation\, Department of Transportation (DOT) and Office of Research at UC.  \nDr. Esfandiari completed her doctoral degree in bioengineering from University of California Los Angeles (UCLA); and earned her MSc in biomedical engineering from University of California Irvine. While at UCLA\, she conducted research at the California Nano-System Institution (CNSI)\, the College of Medicine and the College of Engineering and Applied Sciences. Besides academic training\, she has had three years of experience in industry.  \nDr. Esfandiari has won numerous awards including UC College of Engineering and Applied Science Distinguished Research Award\, the William E. Restemeyer Teaching Excellence Award\, UC Faculty Development Award\, UCLA Unrestricted Fellowship\, UC Irvine Kleist Fellowship\, NSF Fellowship\, and Boeing Scholarship.   \nIf interested\, please email Elizabeth Chesley at e.chesley@northeastern.edu for the seminar link.
URL:https://bioe.northeastern.edu/event/bioe-seminar-series-presents-leyla-esfandiari/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201030T120000
DTEND;TZID=America/New_York:20201030T130000
DTSTAMP:20260424T081617
CREATED:20200916T234143Z
LAST-MODIFIED:20201021T231428Z
UID:2065-1604059200-1604062800@bioe.northeastern.edu
SUMMARY:Bioengineering Works in Progress Student Seminar Series
DESCRIPTION:This virtual seminar series is an opportunity for Bioengineering graduate students to present their research. The first presenter is Ronak Ansaripour from the Carrier lab\, title: “Controlling extracellular matrix environment in guiding 3D Retinal Organoid formation”. The second presenter is Alexander Grath from the Dai lab\, title: “Directly Reprogramming Fibroblasts into Functional Endothelial Cells”. \nPlease email Danielle at d.freshnock@northeastern.edu for the link to the seminar.
URL:https://bioe.northeastern.edu/event/bioengineering-works-in-progress-student-seminar-series-8/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201028T120000
DTEND;TZID=America/New_York:20201028T130000
DTSTAMP:20260424T081617
CREATED:20201014T225847Z
LAST-MODIFIED:20201014T225847Z
UID:2137-1603886400-1603890000@bioe.northeastern.edu
SUMMARY:BioE Seminar Series Presents: Blanka Sharma
DESCRIPTION:Blanka Sharma\, Ph.D. \nAssociate Professor\, Department of Biomedical Engineering\, University of Florida\, Gainesville\, FL  \n“Engineering Biomaterials to Study and Modulate Inflammatory Mechanisms During Tissue Injury and Tumor Progression” \nABSTRACT:   \nExciting advances have been made in the discovery of therapeutic molecules and cells to more effectively treat numerous devastating medical conditions. However\, their successful application in patients is curtailed by significant challenges in effectively delivering these therapeutics where an injury or disease is localized. Dr. Sharma’s research program aims to address these challenges by engineering biomaterials capable of presenting biological signals in a site specific manner within the body. The first part of this talk will focus on drug delivery challenges for the treatment of osteoarthritis. Dr. Sharma will describe her group’s work to overcome barriers to effective drug delivery within joint\, by exploiting specific nanoparticle-extracellular matrix interactions to improve tissue targeting and retention of therapeutic molecules within OA joints. Dr. Sharma will highlight a nanoparticle system that was engineered to target oxidative stress pathways in damaged articular cartilage via scavenging of reactive oxygen species\, resulting in the protection of cartilage viability and tissue structure. The second part of this talk will focus on cell delivery challenges in cancer immunotherapies\, whereby solid tumors create a local immunosuppressive microenvironment that diminish immune cell surveillance and facilitate tumor progression. Dr. Sharma’s laboratory is applying biomaterials to understand how the tumor microenvironment impacts the homing and activation of natural killer (NK) cells\, and developing RNA delivery strategies to harness their cancer killing functions. Mitigating dysfunctional inflammatory mechanisms is key to both tissue remodeling and cancer progression\, and Dr. Sharma’s group works at the intersection of these fields. \nBIOGRAPHY: \nDr. Sharma is an Associate Professor of Biomedical Engineering at the University of Florida. Her research investigates fundamental biomaterial-cell interactions to develop targeted drug and cell delivery systems for applications ranging from tissue repair to cancer therapy. Dr. Blanka Sharma received her undergraduate degree in Chemical Engineering from the University of Waterloo (Waterloo\, Ontario\, Canada)\, her Ph.D. from Johns Hopkins University (Baltimore\, MD) in the Department of Biomedical Engineering\, and her postdoctoral training at the Cleveland Clinic (Cleveland\, OH). Dr. Sharma served as Director of Research for Cartilix Inc. from 2005-2009\, a start-up company based on her doctoral research\, where she worked towards clinical translation of a hydrogel technology for cartilage repair in the knee. After starting her faculty position in 2014 at the University of Florida\, Dr. Sharma was featured by the American Society for Engineering Education as one of “20 Under 40” Outstanding Junior Faculty in the U.S.  More recently\, Dr. Sharma received the National Science Foundation Faculty Early Career Development Program (CAREER) award (2019). In recognition of her teaching\, mentorship\, and research\, Dr. Sharma received the Pramod P. Khargonekar Junior Faculty Award for Excellence in 2020 from the UF College of Engineering. \nIf interested in attending\, please email Elizabeth Chesley at e.chesley@northeastern.edu for the Zoom link.
URL:https://bioe.northeastern.edu/event/bioe-seminar-series-presents-blanka-sharma/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201023T120000
DTEND;TZID=America/New_York:20201023T130000
DTSTAMP:20260424T081617
CREATED:20200916T234055Z
LAST-MODIFIED:20200916T234055Z
UID:2064-1603454400-1603458000@bioe.northeastern.edu
SUMMARY:Bioengineering Works in Progress Student Seminar Series
DESCRIPTION:This virtual seminar series is an opportunity for Bioengineering graduate students to present their research. The first presenter is Kirstie Belanger from the Koppes lab. Title: “Investigating Specific Autonomic Cardiac Innervation in Micro-Physiological Systems”. Jason Derks from the Slavov lab. Title: “Nuclear Relocalization of Proteins in Single Macrophages upon Immunological Challenge”. Please email Danielle at d.freshnock@northeastern.edu for the link to the seminar.
URL:https://bioe.northeastern.edu/event/bioengineering-works-in-progress-student-seminar-series-7/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201021T120000
DTEND;TZID=America/New_York:20201021T130000
DTSTAMP:20260424T081617
CREATED:20201002T235130Z
LAST-MODIFIED:20201002T235130Z
UID:2095-1603281600-1603285200@bioe.northeastern.edu
SUMMARY:BioE Seminar Series Presents: Jennifer Fiegel
DESCRIPTION:Jennifer Fiegel\, Ph.D. \nAssociate Professor and Director of Graduate Studies\, Department of Chemical and Biochemical Engineering\, University of Iowa\, Iowa City IA \n“Oh the Places You’ll Go – Strategies to Treat Pulmonary Bacterial Biofilms and Cell-Penetrating Microbes” \nABSTRACT:   \nLung diseases remain a leading cause of death worldwide\, with significant increases observed in incidence\, morbidity\, and mortality over several decades. The lungs are a critical organ for life\, but are particularly susceptible to injury and airborne infection. Once established in the lungs\, bacterial lung infections can be difficult to eradicate due to a lack of effective antimicrobial drug concentrations at the site of infection\, the formation of bacterial colonies or biofilms in the lungs\, and microbe invasion of lung tissues. The Fiegel lab has been developing a variety of strategies to target antimicrobial treatments directly to the lungs to eliminate bacterial pathogens. In this talk\, I will discuss work from our lab in two areas. First\, I will describe our efforts to develop dry powder aerosols containing a novel combination therapy to enhance the susceptibility of biofilm-forming bacteria to common antibiotics. These therapies combine the action of dispersion compounds to aid the removal of bacteria from the biofilm community\, with that of traditional antibiotics to eliminate the pathogens. While these combinations can eradicate both young and mature biofilms more effectively than antibiotics alone\, testing on patient-isolated bacteria suggests that a clinical course of treatment must be personalized. Second\, I will discuss our efforts to design multi-functional zwitterionic polymer coatings for nanoparticles to reduce biofouling of the nanoparticle surface and enhance adhesion to the lung epithelium. We have observed that polymer coatings help maintain nanoparticle stability in serum and lung fluid\, likely due to strong hydration of the polymers and reduced protein adsorption. However\, while increased particle uptake was observed for zwitterionic-coated particles exposed to serum\, no differences were observed with particles exposed to lung fluid. This suggests that a distinct protein corona is formed in the two fluids which differentially influences particle-cell interactions. \nBIOGRAPHY: \nJennifer Fiegel is an Associate Professor and Director of Graduate Studies in the Department of Chemical and Biochemical Engineering at the University of Iowa. She received her PhD in Chemical and Biomolecular Engineering from Johns Hopkins University in 2004\, then performed postdoctoral studies in the area of aerosol treatments for tuberculosis at Harvard University until 2006. At the University of Iowa\, Dr. Fiegel has developed a multi-disciplinary research program focused on the design of drug delivery systems for the treatment of infections of the lungs and skin. As part of this work\, she examines the behavior of complex lung fluids and particle-fluid interactions. This work has led to over 40 peer-reviewed publications\, book chapters\, and patents; and funding from the NIH and NSF. She has recently expanded her research portfolio to include engineering education research\, with a current focus on engineering ethics. But what she is most proud of is the 14 graduate students and 49 undergraduate students\, more than half of whom are underrepresented in STEM\, that she has mentored in her laboratory since becoming a faculty member. Her emphasis on student development has been acknowledged through teaching awards in both the Colleges of Engineering and Pharmacy\, as well as a Diversity Stimulus Award\, Summer Research Opportunities Mentoring Award\, and Champion for Student Success Award at the university. \nIf interested in attending\, please email Elizabeth Chesley at e.chesley@northeastern.edu
URL:https://bioe.northeastern.edu/event/bioe-seminar-series-presents-jennifer-fiegel/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201016T120000
DTEND;TZID=America/New_York:20201016T130000
DTSTAMP:20260424T081617
CREATED:20200916T234005Z
LAST-MODIFIED:20200916T234005Z
UID:2063-1602849600-1602853200@bioe.northeastern.edu
SUMMARY:Bioengineering Works in Progress Student Seminar Series
DESCRIPTION:This virtual seminar series is an opportunity for Bioengineering graduate students to present their research. The first presenter is Sepideh Tavakoli from the Rouhanifard lab. Title: “Single-molecule detection of modified mRNAs in human cells”. The second presenter is Aleksandra Petelski from the Slavov lab. Title: “Exploring Ribosomal Protein Stoichiometry in Lung Adenocarcinoma Patients”. Please email Danielle at d.freshnock@northeastern.edu for the link to the seminar.
URL:https://bioe.northeastern.edu/event/bioengineering-works-in-progress-student-seminar-series-6/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201014T120000
DTEND;TZID=America/New_York:20201014T130000
DTSTAMP:20260424T081617
CREATED:20200930T000239Z
LAST-MODIFIED:20200930T000239Z
UID:2079-1602676800-1602680400@bioe.northeastern.edu
SUMMARY:BioE Seminar Series Presents: Roger Kamm
DESCRIPTION:Roger Kamm\, Ph.D. \nCecil and Ida Green Distinguished Professor of Biological and Mechanical Engineering\, Massachusetts Institute of Technology\, Cambridge MA  \n“Metastasis on a chip: Effects of intravascular and transendothelial flow” \nABSTRACT:   \nMany CTCs fail to survive the voyage from the primary tumor to the metastatic site\, and die before they can initiate a new tumor.  Others not only survive\, but enter into the tissue where some fraction proliferate and spread.  We studied the effects of vascular flows\, both intravascular (IVF) and transendothelial (TEF) on tumor cell adhesion\, migration and transendothelial migration with the goal of better understanding how flow either promotes or impedes metastasis.  Our results show that CTCs migrate or are dragged in the direction of flow prior to trans-endothelial migration.  We also observe enhanced potential for TEM due to IVF.  TEF\, on the other hand\, has little effect on either migration of CTCs along the luminal surface of the endothelium or their propensity to undergo trans-endothelial migration\, but hastens the process once initiated.  TEF increased the migration speed of tumor cells post-extravasation\, and caused the cells to remain close to the outer endothelial surface. In summary\, both types of flow tend to promote a pro-metastatic phenotype. \nBIOGRAPHY: \nRoger Kamm is the Cecil and Ida Green Distinguished Professor of Biological and Mechanical Engineering at MIT\, where he has served on the faculty since 1978. Kamm has long been instrumental in developing research activities at the interface of biology and mechanics\, formerly in cell and molecular mechanics\, and now in engineered living systems.  Current interests are in developing models of healthy and diseased organ function using microfluidic technologies\, with a focus on vascularization.   \nPlease email Elizabeth Chesley at e.chesley@northeastern.edu for the seminar link.
URL:https://bioe.northeastern.edu/event/bioe-seminar-series-presents-roger-kamm/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201009T120000
DTEND;TZID=America/New_York:20201009T130000
DTSTAMP:20260424T081617
CREATED:20200916T233834Z
LAST-MODIFIED:20200916T233834Z
UID:2062-1602244800-1602248400@bioe.northeastern.edu
SUMMARY:Bioengineering Works in Progress Student Seminar Series
DESCRIPTION:This virtual seminar series is an opportunity for Bioengineering graduate students to present their research. The first presenter is Yifang Liu from the Rouhanifard lab. Title: “Defining cell states based on stochastic transcription”. The second presenter is Max Winkelman from the Dai lab. Title: “Bioengineered Neurovascular Niche Supports Neural Stem Cell Proliferation and Neurogenesis”. Please email Danielle at d.freshnock@northeastern.edu for the link to the seminar.
URL:https://bioe.northeastern.edu/event/bioengineering-works-in-progress-student-seminar-series-5/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201008T120000
DTEND;TZID=America/New_York:20201008T130000
DTSTAMP:20260424T081617
CREATED:20201002T234950Z
LAST-MODIFIED:20201002T234950Z
UID:2094-1602158400-1602162000@bioe.northeastern.edu
SUMMARY:BioE Seminar Series Presents: Aileen Huang-Saad
DESCRIPTION:Aileen Huang-Saad\, Ph.D.\, MBA \nAssociate Professor\, Biomedical Engineering\, Entrepreneurship\, and Engineering Education\, University of Michigan\, Ann Arbor MI  \n“Closing the Gap Between Theory and Practice: Rethinking Engineering Education in Real-Time” \nABSTRACT:   \nDespite 20 years of focus on organizational change and effective educational best practices in STEM higher education\, significant research findings have had minimal influences on practice.  In 2016\, the University of Michigan BME Department sought to disrupt engineering education. Informed by organizational change theory\, we asked: 1) Is there potential for change; 2) what strategies facilitate change\, and 3) how can these strategies be implemented? As a result\, we developed an Instructional Design Sequence\, a new approach to instruction in which students\, post-docs\, and faculty create short Modules that use evidence-based teaching practices to expose BME students to BME professional practice.  This talk describes how the Sequence was conceived of and demonstrates how organizational theory\, entrepreneurship\, and design can be used to inform education practice. The resultant Sequence has the potential to be a transferrable model for transforming engineering education\, offering a new mechanism for integrating career-relevant curriculum into undergraduate curriculum in real-time\, while training future educators in instructional evidence-based practices. \nBIOGRAPHY: \nDr. Huang-Saad is faculty in the Department of Biomedical Engineering and Engineering Education at the University of Michigan. Dr. Huang-Saad has a thirteen-year history of bringing about organizational change in higher education\, leveraging evidence-based practices. She created the U-M BME graduate design program\, co-founded the U-M College of Engineering Center for Entrepreneurship\, launched the U-M National Science Foundation (NSF) I-Corps Node\, and developed the U-M BME Instructional Incubator. She is a canonical instructor for both the NSF and National Institute of Health (NIH) I-Corps Programs. Dr. Huang-Saad has received numerous awards for her teaching and student advising\, including the 1938E College of Engineering Award\, the Thomas M. Sawyer\, Jr. Teaching Award\, the U-M ASEE Outstanding Professor Award\, the International Teaching with Sakai Innovation Award\, and the College of Engineering Outstanding Student Advisor Award.  \nDr. Huang-Saad’s current research areas are entrepreneurship\, innovation\, and transforming higher education.  She is funded by the NSF to explore the influence of the microenvironment of entrepreneurship education on minoritized populations\, entrepreneurial ecosystems\, and fostering graduate student professional development.   \nPrior to joining the University of Michigan faculty\, Dr. Huang-Saad worked in industry gaining experience in new venture biotech\, the defense industry\, and medical device testing.  She has a Bachelor of Science in Engineering from the University of Pennsylvania\, a Doctor of Philosophy from The Johns Hopkins University School of Medicine\, and a Master of Business Administration from the University of Michigan Ross School of Business. \nIf interested in attending\, please email Elizabeth Chesley at e.chesley@northeastern.edu \n 
URL:https://bioe.northeastern.edu/event/bioe-seminar-series-presents-aileen-huang-saad/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201007T120000
DTEND;TZID=America/New_York:20201007T130000
DTSTAMP:20260424T081617
CREATED:20200918T215635Z
LAST-MODIFIED:20200918T215635Z
UID:2068-1602072000-1602075600@bioe.northeastern.edu
SUMMARY:BioE Seminar Series Presents: Wayne Mitzner
DESCRIPTION:Wayne Mitzner\, Ph.D. \nProfessor and Associate Chair for Research in the Department of Environmental Health & Engineering\, Johns Hopkins University Bloomberg School of Public Health\, Baltimore Maryland  \n“New Insights into Lung Anatomy” \nABSTRACT:   \nWe have utilized an optical clearing method to allow visualization of a heretofore undescribed subpleural acinar structural organization in the mammalian lung.  The clearing method enables visualization of the lung structure 40-50 alveoli deep below the visceral pleura in intact inflated lungs.  In addition to confirming previous observations that the immediate subpleural alveoli are uniform in appearance\, we document for the first time that the subpleural lung parenchyma is much more uniformly organized than the internal parenchyma.  Specifically\, below the surface layer of alveoli\, there is a striking parallel arrangement of alveolar ducts that all run perpendicular to the visceral pleural surface.  A three dimensional visualization of alveolar ducts allowed for a calculation of the average inner to outer duct diameter ratio of 0.53 in these subpleural ducts. This unique\, self-organizing parallel duct structure likely impacts both elastic recoil and the transmission of tethering forces in healthy and diseased lungs. \nBIOGRAPHY: \nWayne Mitzner is Professor and Associate Chair for Research in the Department of Environmental Health & Engineering at the Johns Hopkins University Bloomberg School of Public Health.  Dr. Mitzner’s research interests are focused on the structural basis of physiologic and pathologic phenotypes in the lung.  He also has a keen interest in developing methods to assess and quantify pulmonary function in preclinical models\, and has chaired several minisymposia and postgraduate courses in this area.  These functional studies are directed toward investigating the best ways to evaluate pathologic processes after acute and long-term exogenous insults to the lung.  His work has had continuous funding from the NIH for the past 30 years and is supported by over 300 research publications.  \nPlease email Elizabeth Chesley at e.chesley@northeastern.edu for the seminar link.  
URL:https://bioe.northeastern.edu/event/bioe-seminar-series-presents-wayne-mitzner/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20201002T120000
DTEND;TZID=America/New_York:20201002T130000
DTSTAMP:20260424T081617
CREATED:20200916T233727Z
LAST-MODIFIED:20200916T233727Z
UID:2061-1601640000-1601643600@bioe.northeastern.edu
SUMMARY:Bioengineering Works in Progress Student Seminar Series
DESCRIPTION:This virtual seminar series is an opportunity for Bioengineering graduate students to present their research. The first presenter is Shira Tsour from the Slavov lab. Title: “Quantifying rates of mistranslation”. The second presenter is Richard Huffman from the Slavov lab. Title: “Increased Sensitivity\, Reliability\, and Consistency of Single-Cell Proteomics Measurements via Targeted LC-MS/MS Methods”. Please email Danielle at d.freshnock@northeastern.edu for the link to the seminar.
URL:https://bioe.northeastern.edu/event/bioengineering-works-in-progress-student-seminar-series-4/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200930T120000
DTEND;TZID=America/New_York:20200930T130000
DTSTAMP:20260424T081617
CREATED:20200918T191310Z
LAST-MODIFIED:20200918T191310Z
UID:2067-1601467200-1601470800@bioe.northeastern.edu
SUMMARY:BioE Seminar Series Presents: Tara Deans
DESCRIPTION:Tara Deans\, Ph.D. \nAssistant Professor\, Department of Biomedical Engineering\, University of Utah\, Salt Lake City\, Utah  \n“Using synthetic biology to engineer therapeutic devices” \nABSTRACT:   \nSynthetic biology has transformed how cells can be reprogrammed\, providing a means to reliably and predictably control cell behavior with the assembly of genetic parts into more complex gene circuits. Using these approaches\, we are programming stem cells with novel genetic tools to control genes and pathways that result in changes in stem cell fate decisions\, in addition to reprogramming terminally differentiated cells to function as unique therapeutic diagnostic and delivery vehicles. \nBIOGRAPHY: \nDr. Tara Deans received her PhD from Boston University in Biomedical Engineering. Following her postdoctoral training at Johns Hopkins University\, she became an Assistant Professor in Biomedical Engineering at the University of Utah. Currently\, Dr. Deans runs an applied mammalian synthetic biology laboratory where her lab focuses on building novel genetic tools to study the mechanisms of stem cell differentiation for the purpose of directing cell fate decisions. Recently\, Dr. Deans received four prestigious awards to support this area of research: the NSF CAREER Award\, the Office of Naval Research (ONR) Young Investigator Award\, the NIH Trailblazer Award\, and an NIH Director’s New Innovator Award. In addition to her research\, Dr. Deans was named a STEM Ambassador in the STEM Ambassador Program (STEMAP) at the University of Utah to engage underrepresented groups in STEM fields.  \nPlease email Elizabeth Chesley at e.chesley@northeastern.edu for the seminar link.
URL:https://bioe.northeastern.edu/event/bioe-seminar-series-presents-tara-deans/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200925T120000
DTEND;TZID=America/New_York:20200925T130000
DTSTAMP:20260424T081617
CREATED:20200909T190656Z
LAST-MODIFIED:20200909T190656Z
UID:2052-1601035200-1601038800@bioe.northeastern.edu
SUMMARY:Bioengineering Works in Progress Student Seminar Series
DESCRIPTION:This virtual seminar series is an opportunity for Bioengineering graduate students to present their research. The first presenter is Fernando Ivich from the Niedre & Clark lab. Title: “Development of an Optical Instrument for Diffuse Sensing of Fluorescence-Based Circulating Sensors for Human in vivo Drug Monitoring”. The second presenter is Suzanne Stasiak from the Parameswaran lab. Title: “Elucidating force transfer pathways in smooth muscle cell ensembles”. Please email Danielle at d.freshnock@northeastern.edu for the link to the seminar.
URL:https://bioe.northeastern.edu/event/bioengineering-works-in-progress-student-seminar-series-3/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200923T120000
DTEND;TZID=America/New_York:20200923T130000
DTSTAMP:20260424T081617
CREATED:20200918T191127Z
LAST-MODIFIED:20200918T191127Z
UID:2066-1600862400-1600866000@bioe.northeastern.edu
SUMMARY:BioE Seminar Series Presents: Ryan Koppes
DESCRIPTION:Ryan Koppes\, Ph.D. \nAssistant Professor\, Department of Chemical Engineering\, Northeastern University\, Boston\, MA \n“Engineering Innervated Organ Systems” \n ABSTRACT:   \nMicrophysiological systems (MPS) hold the potential to provide benchtop models to investigate fundamental biology and disease while reducing the need for animal models. However\, many conventional in vitro models fail to fully capture the complex cell-cell interactions\, 3D microenvironments\, structural organization\, or vascularization of multicellular organ systems. A key criterion for replicating physiologically relevant architectures in a dish is the ability to compartmentalize discrete cell populations\, extracellular matrix compositions\, and/or mechanical properties\, without meaningfully restricting auto- and paracrine signaling. Traditionally\, compartmentalization within MPS has relied on the use of posts or microtunnels fabricated in silicon-based materials\, often requiring expensive lithographic capabilities. Further\, these methods are commonly limited to confining discrete tissues in the x-y plane. Towards overcoming these limitations\, we have developed a new ‘cut & assemble’ manufacturing technique. We have utilized these new tools to establish a number of MPS platforms to model the cardiovascular system. As part of this talk\, I will highlight the potential of this new technology and how we have applied it to model the heart and the adrenal medulla at the benchtop. Further\, through our work\, I will demonstrate how important the inclusion of neuron populations are for recapitulating organ function. \nBIOGRAPHY: \nDr. Ryan Koppes has been an Assistant Professor at Northeastern University since 2015\, where he has founded the Laboratory for Neuromodulation and Neuromuscular Repair (LNNR). Ryan received his Ph.D. in Biomedical Engineering from Rensselaer Polytechnic Institute (RPI) in Troy\, New York in 2013. His doctoral research with Dr. David Corr focused on soft musculoskeletal biomechanics and tissue engineering. In 2013\, Dr. Koppes joined the Bioelectronics Laboratory with Dr. Polina Anikeeva in Material Science and Engineering at MIT\, where he worked as a Translational Fellow on neural interface technology utilizing a multimaterial thermal drawing process and optogenetics. He was the recipient of the NIH R21 Trailblazer in 2017\, is a co-investigator on a 2019 AHA Innovative Project Award\, an NSF I-Corps\, and is a co-investigator on a 2020 NIH BRAIN Initiative R01 between Northeastern\, UCLA\, and Boston Children’s Hospital. Dr. Koppes also enjoys teaching Chemical Engineering Experimental Design Lab II (Unit Operations II) for senior engineers\, as well as mentoring undergraduates in the laboratory. \nPlease email Elizabeth Chesley at e.chesley@northeastern.edu for the link to the seminar.
URL:https://bioe.northeastern.edu/event/bioe-seminar-series-presents-ryan-koppes/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200922T163000
DTEND;TZID=America/New_York:20200922T173000
DTSTAMP:20260424T081617
CREATED:20200911T183952Z
LAST-MODIFIED:20200911T183952Z
UID:2056-1600792200-1600795800@bioe.northeastern.edu
SUMMARY:BioE Seminar: The Journey of a Serial Entrepreneur by Dr. Amar Sawhney
DESCRIPTION:Entering startups and entrepreneurship can be intimidating as a fresh graduate\, hear from accomplished Dr. Amar Sawhney about success in start-ups and biotech. Currently\, President and CEO of Instylla Inc.\, his resume includes Founder and CEO of Confluent Surgical (acquired by Covidien)\, Chairman of MarketRx (acquired by Cognizant)\, Technology Founder of Focal Inc. (acquired by Genzyme)\, Chairman of Augmenix\, and much more. Dr. Sawhney has founded nine companies and was among those named a Champion of Change by the Obama Administration. Learn from the stories and advice of a notable “Immigrant Innovator” on being a serial entrepreneur. \n\nJoin Zoom Meeting \n\n\nMeeting ID: 992 9731 3601 \n\n\nPasscode: 121417
URL:https://bioe.northeastern.edu/event/bioe-seminar-the-journey-of-a-serial-entrepreneur-by-dr-amar-sawhney/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200918T120000
DTEND;TZID=America/New_York:20200918T130000
DTSTAMP:20260424T081617
CREATED:20200909T190604Z
LAST-MODIFIED:20200909T190604Z
UID:2051-1600430400-1600434000@bioe.northeastern.edu
SUMMARY:Bioengineering Works in Progress Student Seminar Series
DESCRIPTION:This virtual seminar series is an opportunity for Bioengineering graduate students to present their research. The first presenter is Nathaniel Silvia from the Dai lab. Title: “Characterizing glioblastoma pathology by in vitro modeling”. The second presenter is Tengfei He from the Bajpayee lab. Title: “Multi-arm Avidin Nano-construct for Intra-cartilage Delivery of Small Molecule Drugs”. Please email Danielle at d.freshnock@northeastern.edu for the link to the seminar.
URL:https://bioe.northeastern.edu/event/bioengineering-works-in-progress-student-seminar-series-2/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200911T120000
DTEND;TZID=America/New_York:20200911T130000
DTSTAMP:20260424T081617
CREATED:20200908T192755Z
LAST-MODIFIED:20200908T192755Z
UID:2047-1599825600-1599829200@bioe.northeastern.edu
SUMMARY:Bioengineering Works in Progress Student Seminar Series
DESCRIPTION:This virtual seminar series is an opportunity for Bioengineering graduate students to present their work. Presenters are listed below: \nFrederick Sebastian from the Amini lab \nTitle: “Computational Approaches to Assess Irides in Glaucomatous Eyes” \nChia-Ming Wang from the Carrier lab \nTitle: “Development of a gut-microbiome mesofluidic device allowing facile visualization of intestinal mucosal barrier interface” \nPlease email Danielle at d.freshnock@northeastern.edu for the link to the seminar.
URL:https://bioe.northeastern.edu/event/bioengineering-works-in-progress-student-seminar-series/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200825T120000
DTEND;TZID=America/New_York:20200825T130000
DTSTAMP:20260424T081617
CREATED:20200824T182231Z
LAST-MODIFIED:20200824T182231Z
UID:2041-1598356800-1598360400@bioe.northeastern.edu
SUMMARY:Bioengineering Works in Progress Seminar Series
DESCRIPTION:This virtual seminar series is an opportunity for Bioengineering graduate students and postdocs to present their work. \nPlease reach out to Prachi at pr.shah@northeastern.edu for the link to the seminar
URL:https://bioe.northeastern.edu/event/bioengineering-works-in-progress-seminar-series-15/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200818T120000
DTEND;TZID=America/New_York:20200818T130000
DTSTAMP:20260424T081617
CREATED:20200810T173710Z
LAST-MODIFIED:20200810T173710Z
UID:2037-1597752000-1597755600@bioe.northeastern.edu
SUMMARY:Bioengineering Works in Progress Seminar Series
DESCRIPTION:This virtual seminar series is an opportunity for Bioengineering graduate students and postdocs to present their work. Edward Xu and Mahsa Sadeghian will be presenting. \nPlease reach out to Prachi at pr.shah@northeastern.edu for the link to the seminar
URL:https://bioe.northeastern.edu/event/bioengineering-works-in-progress-seminar-series-14/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200811T120000
DTEND;TZID=America/New_York:20200811T130000
DTSTAMP:20260424T081617
CREATED:20200724T004423Z
LAST-MODIFIED:20200724T004423Z
UID:2028-1597147200-1597150800@bioe.northeastern.edu
SUMMARY:Bioengineering Works in Progress Seminar Series
DESCRIPTION:This virtual seminar series is an opportunity for Bioengineering graduate students and postdocs to present their work. Rahul Ragunathan and Ester Comellas will be presenting. \nPlease reach out to Prachi at pr.shah@northeastern.edu for the link to the seminar
URL:https://bioe.northeastern.edu/event/bioengineering-works-in-progress-seminar-series-13/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200804T120000
DTEND;TZID=America/New_York:20200804T130000
DTSTAMP:20260424T081617
CREATED:20200724T004318Z
LAST-MODIFIED:20200724T004318Z
UID:2026-1596542400-1596546000@bioe.northeastern.edu
SUMMARY:Bioengineering Works in Progress Seminar Series
DESCRIPTION:This virtual seminar series is an opportunity for Bioengineering graduate students and postdocs to present their work. Shadi Emam and Muhammad Ali will be presenting. \nPlease reach out to Prachi at pr.shah@northeastern.edu for the link to the seminar.
URL:https://bioe.northeastern.edu/event/bioengineering-works-in-progress-seminar-series-12/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
BEGIN:VEVENT
DTSTART;TZID=America/New_York:20200728T120000
DTEND;TZID=America/New_York:20200728T130000
DTSTAMP:20260424T081617
CREATED:20200724T004229Z
LAST-MODIFIED:20200724T004349Z
UID:2027-1595937600-1595941200@bioe.northeastern.edu
SUMMARY:Bioengineering Works in Progress Seminar Series
DESCRIPTION:This virtual seminar series is an opportunity for Bioengineering graduate students and postdocs to present their work. Shikhar Mehta and Anh Phong Tran will be presenting. \nPlease reach out to Prachi at pr.shah@northeastern.edu for the link to the seminar.
URL:https://bioe.northeastern.edu/event/bioengineering-works-in-progress-seminar-series-11/
ORGANIZER;CN="Bioengineering":MAILTO:bioe@northeastern.edu
END:VEVENT
END:VCALENDAR