Motor control and learning, variability and stability, virtual rehabilitation, dynamic modeling, rhythmic and discrete movements as primitives for action
Cellular and molecular mechanobiology, mechanomedicine, and mechanohealth; cancer cell biology and mechanics; stem cell biology and mechanics; mechanomemory and mechanoresilience, mechanobiotechnologies and their applications to cells, tissues, and organisms
Our group investigates biomolecules at the single-molecule level. We develop nanopore-based and other nanotechnology-based methods for probing the structure and dynamic behavior of biomolecules. We employ optical waveguides and single-molecule enzymatic approaches for RNA sequencing, and utilize engineered nanopore sensors for applications in single-molecule proteomics. We are experimentalists, but we also use advanced computational tools to perform big data analysis.
dynamics of large-scale molecular machines, working to identify the physical principles that guide biomolecular dynamics, using molecular simulation approaches to interpret experimental data from a wide range of techniques, including biochemical, small-angle X-ray scattering and cryogenic electron microscopy