Innovations in translational medical imaging devices to better diagnose cancers, low-cost point-of-care diagnostic tools to delivery life-saving medicines to the resource-poor regions, and high performance computing tools to facilitate the development of the next-generation imaging methods
Entrepreneurship education microenvironments and their impact on the engagement of diverse populations, the influence of I-Corps on university ecosystems, and transforming BME education through instructional design
Physical modeling of cancer progression, metastasis and interaction with the immune system. Most recent interests include the role of metabolic plasticity in these processes and the co-evolution of the tumor and the adaptive immune system. Other areas include spatial organization of the actin cytoskeleton, the mechanics of collective cell motility, and the analysis of genetic circuits involved in cell fate decisions.
Computational systems biology, an integration of mathematical modeling and bioinformatics for studying gene regulatory networks, single cell genomics, epithelial-mesenchymal transition, coarse-graining, reverse engineering, machine learning, stochasticity and heterogeneity in gene expression
Using computational methods including Monte Carlo methods, molecular dynamics simulations, and molecular docking calculations to obtain a fundamental understanding of molecular interactions that occur at biological interfaces, such as the pulmonary surfactant system in the lungs
Developing chemical approaches to track and quantify important RNA processing events and modifications in single cells; DNA: protein interactions that drive differences in gene expression; understanding differences in RNA expression and the impacts on disease and development